I recently had a friend explain their pain with fibromyalgia. It was explained: over work yourself in a day, past the point of muscles burning and exhaustion setting in, then the next day when you’re unable to move because every muscle burns and aches that’s how it feels. I’ve had that kind of pain before and it went away after a few days, however, to have it chronically would be absolutely unbearable.
WebMD describes Fibromyalgia in this manner: Fibromyalgia-related pain is pain that causes you to ache all over. You have painful places on your body that hurt no matter what medication you take. Your muscles may feel like they have been overworked or pulled even though you haven’t exercised. Sometimes, your muscles will twitch. Other times they will burn or ache with deep stabbing pain. This kind of pain makes life very difficult (next to unbearable). Sleep and exercise are often out of the question. In a nutshell that’s pretty much exactly what my friend described. I hope that these two blogs will help even a single person with their fight against this debilitative disease.
To all of you my heart goes out to you and may God Bless each and every one.
People with Fibromyalgia suffer from “Chronic Pain”. As we know chronic pain is pain that persist longer than normally expected like with an injury. When pain becomes chronic our bodies react in several ways. Thru time researchers have realized that chronic pain is associated with abnormalities in the brain hormones, low energy, mood disorders, muscle pain, and impaired mental and physical performance due to omega-3 deficiencies.
Changes occur in your body due to this chronic pain which ables the body’s sensitivity to pain to increase causing the chronic pain to worsen. Your brain is now sending signals thru the central nervous system to other parts of the body that would normally not hurt and telling them to hurt.
In my previous blog (Vital HP) I talked about how omega-3s in phospholipid form are very important to help the brain work properly and talk to the central nervous system. That was the first of two major areas of omega-3 fatty acids influence in fighting against fibromyalgia and other chronic inflammation.
It was shown that omega-3 fatty acids in phospholipid form play a major role in helping those with chronic inflammation and chronic pain because of its importance to neuronal membranes. Omega-3s are essential components of Central Nervous System membrane phospholipid acyl chains and are therefore critical to the overall structure and function of neuronal membranes (PubMed). Proteins are embedded in the lipid bi-layer of the cell and the structure of these cells is very sensitive to the lipid components. These proteins have vital jobs. They act as transporters and receptors. Omega-3 fatty acids in phospholipid form can alter membrane fluidity. The best possible fluidity, influenced by EFA’s is required for neurotransmitter binding and the signaling within the cell. EFAs can act as second messengers within and between neurons. (PubMed)
Krill oil is the only dietary supplement on the market that carries omega-3 DHA and EPA in phospholipid form. Krill oil is also the only dietary supplement on the market that has the added benefit of antioxidant power from its natural source of astaxanthin found in krill itself. This is the second most important area for omega-3 influence for fighting against fibromyalgia.
The second area where omega-3 fatty acids have substantial impact is thru the cytokine modulation. Cytokine Modules are proteins that are produced by cells. Cytokines interact with cells of the immune system in order to regulate the body's response to disease and infection. Cytokines also mediate normal cellular processes in the body. Different types of immune cells and proteins do different jobs. Cytokines are among those proteins.
However, to understand inflammation, you must understand the role that cytokines play.
Cytokines are released by cells into the circulation or directly into tissue. The cytokines locate target immune cells and interact with receptors on the target immune cells by binding to them. The interaction triggers or stimulates specific responses by the target cells.
Overproduction or inappropriate production of certain cytokines by the body can result in disease. AJCN found that interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) are produced in excess in rheumatoid arthritis where they are involved in inflammation and tissue destruction.
These pro-inflammatory immune chemicals can have direct and indirect effects on the Central Nervous System. Researchers have studied the activities of these cytokines and have found that they include lowered neurotransmitter precursor accessibility, stimulation of the hypothalamic –pituitary axis, and alterations of the metabolism of neurotransmitters and neurotransmitter mRNA. (PubMed)
Cytokines pro-inflammatory immune chemicals need to be suppressed or stopped when they are preforming incorrectly. Omega-3 fatty acids, especially EPA have been found to inhibit proinflammatory cytokines. The anti-inflammatory role of omega-3 fatty acids have heavy influence on brain receptors and are extremely vital to the components of the central nervous system. Both of which play important roles themselves in protecting the body against chronic inflammation and disease especially fibromyalgia.
However as we mentioned in the first part of this blog its important the omega-3s be in phospholipid form because of their crucial role in the overall structure and function of neuronal membranes. Not all omega-3s are equal. Many are in Triglyceride form. Triglyceride form is fine and can help better your health. However, omega-3 fatty acids in triglyceride form are unable to work directly with the cell membranes of the body. It must in fact pass thru the liver before starting to break down to even allow for the DHA and EPA to enter the cells. This is why some people are finding that fish oil, flaxseed and other omega-3 fatty acids are not helping them. It’s an immense amount of work for the body to break these omega-3 fatty acids down and oxidation of these omega-3s has already begun therefore your body is not getting the potent amount of bio-available nutrients it needs to fight chronic inflammation, chronic pain , cancer or diseases. It’s very important that your omega-3 fatty acid intake is supplemented with an antioxidant such as Vitamin A or Vitamin E.
In this case I recommend Krill oil because it naturally contains the most powerful antioxidant on the earth, Astaxanthin. Dietary antioxidants such as Astaxanthin can influence omega-3 level of quality.
When the body is deficient in omega-3s lipid peroxidation and oxidative stress occurs. Oxidative stress is a broad term used to describe the steady level of oxidative damage in a cell, tissue, or organ. This damage can affect a specific molecule or the entire organism. Free radicals and peroxides represent a class of molecules that are derived from the metabolism of oxygen and exist inherently in all aerobic organisms.
Many symptoms of chronic inflammation, chronic pain and depression have strong correlations with lipid peroxidation. Dietary antioxidants such as astaxanthin are well known for their antioxidant defense systems and research does show that they have a major influence on omega-3 value. Omega-3 fatty acids especially those in phospholipid form have been proven to decrease lipid peroxidation rapidly.
Krill oil with its potent bio-availability of omega-3 DHA and EPA due to its natural antioxidant astaxanthin is showing to be the best effect dietary supplement on the market to fight against chronic inflammation, chronic pain and other inflammatory diseases. Phospholipid form is by far the best most efficient way to get nutrients your body needs rapidly and effectively. Triglyceride form such as fish oil is still effective but at a price (time).
We have two very important sides to help fight against fibromyalgia, Omega-3 DHA and EPA phospholipid form and antioxidant supplementation (astaxanthin).
Krill oil contains both. I recommend you give Krill oil a try and see for yourself.